Exercised

An evolutionary and human-biology look at why movement matters, why exercise feels difficult, and how to make it more rewarding.

A 2025 network meta-analysis found that aerobic, mind-body, and resistance exercise interventions were associated with lower depressive-symptom scores than control conditions in adults with clinically diagnosed depression, although effects varied by exercise mode. A pragmatic trial found depressive symptoms decreased in both usual care and usual care plus exercise, while adherence to the prescribed exercise program was limited. In older adults with amnestic mild cognitive impairment, a randomized trial found no cognitive advantage of moderate-high intensity aerobic exercise over lower-intensity stretching and balance exercise, so the supplied evidence does not establish broad disease-prevention or cognitive-protection claims.